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Sneeze patrol
Are you a candidate for allergies?

By CANDACE DOYLE

May 2007

A full 10 percent of the United States population has an allergic disease like hay fever and 15 million Americans have asthma, says Dr. Mary Jo Rolfes-Lo, an allergist with ProHealth Care Medical Center in Waukesha.

Hay fever and asthma are among the most prevalent allergies, too, says Dr. James Pugely, an allergist at Columbia St. Mary’s in Milwaukee. "The most common ones are airborne allergies — pollen, dust mites, pets and mold. That’s followed by foods and medication. In this area, everyone would talk about hay fever in late summer and early fall. Also in the fall of the year, the dust mites and molds do very well and tend to cause a lot of asthma problems."

Rolfes-Lo groups the allergies in two categories: seasonal, such as reactions to pollen in spring, and year-round, such as reactions to mold, pet dander and dust mites.

Meanwhile, Dr. Tad Johnson, an allergist with Allergy and Asthma Clinic of Wisconsin, categorizes them as indoor (pet dander, dust mites and mold) and outdoor (outdoor molds and allergens such as pollen in spring and ragweed in fall) allergies.

Then there are less frequent contact allergies, such as reactions to foods — with an adverse reaction to peanuts being the most common — and medication, with penicillin leading the list of drugs causing a negative reaction.

But whichever way allergies are categorized, they are treated in remarkably similar ways. "The oldest treatment is avoidance," says Johnson. "If you have a cat and you’re allergic to cats, get a new home for the cat."

Other medical options include the use of antihistamines, nasal cortisone and allergy eye drops. "These treatments have been stable over the years," he says.

While traditional, Pugely says today’s antihistamines are less sedating and longer lasting. Some newer medications, like XOLAIR to treat allergic asthma, work to block immunoglobulin E production, an underlying cause of a reaction. "Injection therapy is probably more common," he says. "It points the way in the future to treating the immune system."

According to Rolfes-Lo, a new antihistamine that’s not yet FDA-approved is coming out this summer and promises better control of allergy symptoms. In addition, there are new asthma inhalers with fewer side effects on the horizon, as well as sublingual immunotherapy that’s similar to an allergy shot except it’s placed under the tongue and is in higher doses.

But before treatment, a correct diagnosis needs to be made. That can be done through skin tests — pricking the skin with a comb-like tool that contains the allergen; intradermal tests, in which the allergen is placed under the skin with a needle if the skin test is negative; and what’s called a CAP test that measures an allergen’s antibodies in the blood.

Additionally, and before any testing is done, a thorough medical history of the patient is needed, says Dr. Kristen Volkman, an allergist with Wheaton Franciscan Medical Group. "There probably is some genetic predisposition to allergies," she adds.

For example, she says if both parents are allergic, there’s a 60 percent chance that their child will be too. If only one parent is, there’s a 30 percent chance. And if neither parent has allergies, the chances that their child will drops to 15 percent. However, she notes there’s a theory that says the cleaner that environment, the more prone one would be to allergies. It’s called the hygiene hypothesis, and it states that a lack of early exposure to infectious agents increases susceptibility to allergies. "They do run in families," Volkman says. "But it’s also a product of your environment."

Peanut woes

Ninety-percent of all food allergies are caused by a handful of allergens, with peanuts the most prevalent, says Dr. Mary Jo Rolfs-Lo, an allergist with ProHealth Care Medical Center in Waukesha. "Food allergies are rare, but peanuts make up two-thirds of them," says Dr. Tad Johnson, an allergist with Allergy and Asthma Clinic of Wisconsin. And the number of people allergic to peanuts is on the rise. While there’s no known reason, he says "Part of it may be that the peanut is introduced early in the diet of the child. The digestive system is still immature and hasn’t developed a resistance to peanuts." For that reason, he suggests not introducing peanuts — including peanut butter — to children until they are 3 or 4 years old.

Deadly reactions

Being stung by a bee can be deadly for the person allergic to its venom, says Dr. James Pugely, an allergist who practices at Columbia St. Mary’s in Milwaukee. "But the one that seems to be the most dangerous is the peanut." Life-threatening symptoms include a swelling in the throat, a severe drop in blood pressure and the lungs filling with liquid. Reducing exposure is the ideal way to avoid a reaction. But in the event of contact, Pugely says treatment to block a reaction is needed. "The emergent treatment is to have access to epinephrine. Obviously, schools keep it, day cares keep it now. That should be administered as quickly as possible." Then, see a doctor. "If you’ve had a reaction, you have to get medical care."

Pet lover

Shelby Therkelsen, 11, loves horses — so much so that she saved up her hard-earned dollars to help buy one.

Unfortunately, that’s when Therkelsen’s allergic reaction accelerated.

Sandy Nelsen, her mother, says Therkelsen would be sneezy if she spent a lot of time around horses and hay. In fact, when Misty joined their family, Therkelsen would go through a box of tissue if she spent the afternoon with her horse.

"I would sneeze a lot, I’d get a runny nose, and my eyes would get red and itchy," Therkelsen says.

A skin test on her back revealed that Therkelsen was, indeed, allergic to horses. And today she’s taking Zyrtec, an antihistamine. "It keeps her from having such a severe reaction," Nelsen says.

She also takes Patanol — prescription eyedrops. "The drops help with the redness, the itching and the swelling," says Nelsen, adding that the treatments have relieved 80 to 90 percent of the symptoms.

And for Therkelsen, medication was the only option, as she told her mother, "I’m not getting rid of the horse."

Foodie

Casey Zwettler, 27, has loved peanut butter since he was a kid.

So when he recently starting having a reaction to it, he was more than concerned.

"I had a swollen lip and some itchy hands, and a little bit of hives," he says. "I thought it was the peanut butter. That was something that stuck out in my head."

He knew that peanuts were a fairly common food allergen, and he tried over-the-counter medications to alleviate the symptoms. That worked somewhat, but still the symptoms persisted. "After it happened a few times, I wanted to be sure what it was," he says.

At his first trip to an allergist, Zwettler’s medical history was

documented. With it, he was asked to recount what he had eaten prior to his reactions.

That was followed by a skin prick test on his back, which came back positive to peanuts — but not overwhelmingly so. And a subsequent blood test came back negative. "Then we weren’t sure," he says.

Confusing matters more was when he had a similar reaction but had not consumed any peanut butter.

Now, he’s undergoing a food challenge, in which he’ll eat peanut butter in increasing amounts every day for two weeks to see if that is definitely the cause. "We’re definitely going to talk and see what else we can do," Zwettler says.