MILWAUKEE – The
Human and Molecular Genetics Center at the Medical College of
Wisconsin, in collaboration with Illumina, is selected as one of two
National Institutes of Health genomic sequencing sites for the
Undiagnosed Disease Network.
This network was
created to use DNA sequencing and other strategies to advance
laboratory and clinical research as well as aid in the diagnosis and
treatment of patients with rare diseases.
Howard J. Jacob,
Ph.D., the professor of genetics at the medical college and director
of the project, is the primary investigator on the four-year $2.5
Ph.D., a clinical director at Illumina, is co-primary investigator,
along with Elizabeth Worthey, Ph.D., assistant professor of
pediatrics and director of genomic informatics at the medical
Disease Network identified six clinical sites in summer 2014 in
which patients with rare disease will be identified for genetic
center at the medical college is tasked with performing whole genome
sequencing on 1,650 patients and family members referred by those
sites, over the period of four years.
as an industry collaborator will be to develop protocols,
algorithms, quality improvements and to act as a partner in
streamlining the sequencing process.