Western diet could increase your risk of deadly sepsis,
according to a new study.
In a study
published in the Proceedings of the National Academy of
Sciences of the United States of America, researchers found
the traditional Western diet, which is high in fats and
sucrose and low in fiber, could have an impact on sepsis.
first listed author, Dr. Brooke Napier, told the Sun, “It
looks like the (Western) diet is manipulating immune cell
function so that you’re more susceptible to sepsis, and then
when you get sepsis, you die quicker.”
Sepsis is an
immune system response to infection that causes organ failure.
It is the 11th-most common cause of death around the world,
according to the study.
found mice who ate a Western diet had “increased sepsis
severity and poorer outcomes.” The mice had a higher
baseline level of inflammation and “increased
sepsis-associated immunoparalysis” compared to mice that ate
we found that the WD-dependent increase in sepsis severity and
higher mortality is independent of the microbiome, suggesting
that the diet may be directly regulating the innate immune
system through an unknown mechanism,” according to a
statement from the researchers.
Napier said the
team will investigate if certain fats in the Western diet
cause the immune system change.
The study was
written by Brooke A. Napier, Marta Andres-Terre, Liliana M.
Massis, Andrew J. Hryckowian, Steven K. Higginbottom,
Katherine Cumnock, Kerriann M. Casey, Bereketeab Haileselassie,
Kyler A. Lugo, David S. Schneider, Justin L. Sonnenburg and
Denise M. Monack.