Is vitamin D the next
big thing in heart health?
"I'm cautiously optimistic," says
Dr. Amit Khera, Director of the Preventive Cardiology Program
at University of Texas-Southwestern Medical Center and
chairman of the American Heart Association's State Advocacy
Committee. Some studies indicate that people with higher
levels of vitamin D have a lower risk of heart disease and
stroke, along with fewer risk factors such as high blood
pressure and diabetes.
Now that could mean that vitamin D is just
"keeping company" with other factors that lead to
healthier hearts, Khera notes. But it makes sense biologically
to him because the liners to the arteries have vitamin D
receptors.
"It may be interacting with the
arteries to make them healthy. I do think it's quite plausible
that normalizing vitamin D may help lower heart disease risk.
The evidence is not definitive, but it is pretty
suggestive."
Khera says he hesitates to jump to
conclusions after feeling "burned" with previous
promises of vitamin E and hormone replacement therapy.
About 25 to 50 percent of the population has
some degree of vitamin D deficiency, he says. He recommends
speaking to your physician about whether you need to take
vitamin D and the appropriate dose depending on your blood
levels, age, and risks.
Although there are generally few side
effects, he cautions that very large amounts can lead to
excessive calcium levels, which could result in kidney stones,
confusion, and lead to various aches and pains.
Vitamin D is produced through the skin by
exposure to sunlight. With people spending less time in the
sun and using sunscreens when they are outside, they need to
get more of their vitamin D through supplements or a diet of
fatty fish, eggs and fortified milk, he says.
In addition, obesity can lower vitamin D
levels, with fat tissue preventing the vitamin from
circulating in the blood.
"I think we have to be a little
cautious about overdoing it," he says. "It's not
some miracle. But the cost is minimal and there's not a lot of
toxicity. And if the evidence continues to accumulate that
vitamin D plays a role in heart health, we may become more
aggressive about prescribing it to our patients."