INDIANAPOLIS — Reggie Wayne asked the Indianapolis Colts equipment manager to track down some orange gloves for him to honor ailing coach Chuck Pagano. He then turned those gloves into a day no one will soon forget.

Wayne caught 13 passes for 212 yards and the biggest one of all was a 4-yard reception where he fought his way through two defenders for the game-winning touchdown in the Colts’ 30-27 win over the Green Bay Packers on Sunday at Lucas Oil Stadium.

The Colts not only erased an 18-point deficit, but they accomplished their improbable goal of earning a game ball for Pagano, who is in the hospital fighting acute promyelocytic leukemia.

“This is for Chuck,” Wayne said after he left an emotional, tear-filled Colts locker room.

Wayne has been friends with Pagano since they were at the University of Miami together, Wayne as a player and Pagano as an assistant coach.

“I wasn’t sure how it would go with being fined,” Wayne said. “If they fine me, they fine me. I feel like that’d be a terrible thing to do with everything going on. But I’d take their fine and go do it for Chuck.”

Indianapolis Colts tight end Dwayne Allen (83) goes in for an 8-yard touchdown reception while being defended by Green Bay Packers cornerback Tramon Williams during the second half.

The Colts won the game on a 13-play, 80-yard drive directed by rookie quarterback Andrew Luck, who finished 31 of 55 passing for a career-best 362 yards and two scores.

Luck hit Wayne five times on the game-winning drive, including one third-down play where he escaped Packers linebacker Clay Matthews. Luck also ran for a third-down conversion to set up the final touchdown with 35 seconds left.

The Colts trailed 21-3 at halftime before they came back with a furious second half. Green Bay’s Mason Crosby missed a potential game-tying 51-yard field goal at the end.

“Greatest win I’ve ever been a part of,” interim coach Bruce Arians said. “A storybook ending, and we got a game ball for Coach Pagano.”

Green Bay Packers tight end Tom Crabtree is tackled by Indianapolis Colts linebacker Moise Fokou during the first half.

After spotting Green Bay a 21-3 lead, the Colts defense put substantial pressure on Green Bay quarterback Aaron Rodgers. They sacked him five times and hit him six other times. Cory Redding, one of the players closest to Pagano because of their time in Baltimore together, had two sacks. Dwight Freeney (playing for the first time since the season opener), Robert Mathis and Moise Fokou also had sacks.

“A band of brothers just came together,” Arians said. “This team overcame something no one gave them a shot to do. Now we have to carry it over.”

Colts owner Jim Irsay left after the game to present Pagano with the game ball at the IU Health Simon Cancer Center. Arians said some of the players hoped to visit the coach later Sunday night.

Indianapolis Colts interim head coach Bruce Arians walks onto the field before the start of an NFL football game between the Indianapolis Colts and Green Bay Packers in Indianapolis, Sunday, Oct. 7, 2012. Arians is coaching in place of Colts head coach Chuck Pagano who was diagnosed with acute promyelocytic leukemia.

Stunned Packers, now 2-3, looking for answers

GREEN BAY, Wis. - The Green Bay Packers are looking for some answers.

The offense looks nothing like it did in 2011. Their defense looks entirely too much like last year's group. And kicker Mason Crosby missed a pair of 50-yard field goals Sunday in a dispiriting 30-27 loss at Indianapolis.

It all adds up to a 2-3 record, putting the Packers below .500 at this point in the season for the third time in coach Mike McCarthy's seven-year tenure. In 2006, the team ended the year at 8-8. In 2008, the Packers ended up 6-10.

Injuries haven't helped. Wide receiver Greg Jennings who missed Sunday's loss with a groin injury and running back Cedric Benson left the game with a sprained foot.

The next game is at Houston on Sunday night.